GLP-1 Tirzepatide and Retatrutide weight loss injections — supervised by Dr. Guillermo Castillo, Board Certified Family Medicine. Real results, 4 convenient Southern California locations.
Medical weight loss is a physician-supervised program that uses FDA-recognized medications, clinical monitoring, and personalized dosing to help you lose weight faster and more safely than diet and exercise alone. At The Hydro Drip Bar in Temecula and across Southern California, our medical weight loss program centers on GLP-1 receptor agonist injections — the most effective class of weight loss medications ever studied.
GLP-1 stands for glucagon-like peptide-1, a hormone your gut naturally produces after eating. When replicated pharmacologically at higher doses, it powerfully suppresses appetite, slows gastric emptying, and improves blood sugar regulation — leading to consistent, sustained fat loss without the hunger, crashes, or rebounds associated with fad diets.
We offer two cutting-edge GLP-1 medications, both far more effective than older options like semaglutide (Ozempic/Wegovy). Here's how they compare:
Tirzepatide (brand name Mounjaro/Zepbound) is a dual GIP/GLP-1 receptor agonist — the current gold standard for most patients. It's our most popular option, starting at just $299/mo with a new client intro price of $99 for your first month (4 weekly 2.5mg shots). Clinical studies show 20–22% average body weight loss over 72 weeks.
Retatrutide is a next-generation triple receptor agonist (GLP-1 + GIP + Glucagon), currently the most powerful weight loss peptide available. Early trials show up to 24% body weight reduction. Starting at $399/mo, it's the right choice for patients who need maximum results or haven't responded as expected to other GLP-1 medications.
There are a growing number of medical weight loss clinics in the Temecula and San Diego area — so why are hundreds of patients choosing The Hydro Drip Bar? Because we combine clinical credibility with walk-in accessibility across 4 locations, and we're the only Southern California GLP-1 clinic that pairs weight loss injections with IV hydration therapy to offset common side effects like nausea and fatigue.
Every program is supervised by Dr. Guillermo Castillo, Board Certified Family Medicine, and administered by our team of experienced Registered Nurses — founders Ricky Sarmiento RN,BSN and Mary Grace Sarmiento RN,BSN. No telehealth-only clinics. No unmonitored mail-order injections. Real clinical oversight, in person, at our Temecula, Mira Mesa, National City, and Escondido locations.
Our Temecula location at 27420 Jefferson Ave, Suite 101-A is the original Hydro Drip Bar clinic and our most visited weight loss center. We serve patients from Temecula, Murrieta, Menifee, Wildomar, Lake Elsinore, and the Inland Empire. Walk-ins are welcome and same-day consultations are available.
Temecula's GLP-1 market is growing fast — with competitors like Serenity MD, Tri Valley Medical, and Vellure Med Spa all offering weight loss programs. What sets us apart is our $99 new client pricing, no long-term contracts, and the ability to combine IV therapy with your weight loss visit in a single appointment.
San Diego County residents can access our GLP-1 weight loss program at two convenient locations: Mira Mesa (8160 Mira Mesa Blvd, Suites 111 & 112) serving North San Diego, Scripps Ranch, Kearny Mesa, and Sorrento Valley — and National City (3030 Plaza Bonita Rd, Westfield Plaza Bonita) serving Chula Vista, Bonita, Eastlake, and South San Diego.
Both San Diego locations offer the same medically supervised GLP-1 program with the same $99 new client pricing. No need to drive to Temecula — get your weekly injection close to home or work.
Our newest location at 272 E Via Rancho Pkwy, inside Glow and Beauty Medspa brings medically supervised GLP-1 weight loss to North San Diego County. We serve patients from Escondido, San Marcos, Vista, Rancho Bernardo, and Poway. Same program, same pricing — now even closer to North County residents.
Southern California's only IV wellness clinic that pairs GLP-1 weight loss with IV hydration therapy.
Dr. Guillermo Castillo, Board Certified Family Medicine, oversees all GLP-1 programs. Every patient receives a proper medical screening before starting — unlike telehealth-only services that skip this step.
Temecula, Mira Mesa San Diego, National City, and Escondido — most clients are within 20 minutes of a location. Walk-ins welcome. No appointment needed for follow-up injections.
Your first month of Tirzepatide is just $99 — saving $200 off the regular $299/mo price. No hidden fees, no long-term contracts. Cancel or pause anytime.
The only clinic in SoCal that lets you combine your GLP-1 injection with an IV drip in one visit. Our Myers Cocktail and Energy Boost IVs help combat Tirzepatide side effects — faster results with fewer setbacks.
Founders Ricky and Mary Grace Sarmiento are both Registered Nurses (RN, BSN). Your injection is always performed by licensed clinical staff — not medical assistants or unlicensed technicians.
Our client Arlene lost 75 lbs on our Tirzepatide program. Real, documented results from real Southern California patients — not stock photo testimonials.
"I had tried everything for years. Within the first month on Tirzepatide at The Hydro Drip Bar, the cravings just stopped. The team made it so easy — walk in, get my shot, and go. 75 pounds later, I'm a completely different person."
GLP-1 medications are not magic — they work with your biology to make eating less feel effortless. Here's what the clinical evidence and our client outcomes show:
From consultation to your first injection — start losing weight this week.
Walk in or book online at any of our 4 Southern California locations. A brief medical screening ensures GLP-1 is right for you.
Select Tirzepatide ($299/mo, new clients $99) or Retatrutide ($399/mo). Our RN team explains dosing, expectations, and timeline.
Visit any location weekly for your subcutaneous injection. Add an IV drip to combat side effects and accelerate results.
Track your progress monthly. Most clients see measurable loss within 3–4 weeks. Continue or taper as you hit your goal weight.
No hidden fees. No long-term contracts. The most transparent GLP-1 pricing in Southern California.
| Feature | The Hydro Drip Bar | Typical Competitor |
|---|---|---|
| New Client Pricing | $99 first month | $299–$499/mo |
| MD Supervision | ✓ Board Certified | Varies (often NP only) |
| RN-Administered | ✓ Always | Sometimes MA |
| IV Therapy Add-On | ✓ Same visit | ✗ Not offered |
| Walk-Ins Welcome | ✓ All locations | Usually appointment only |
| Southern CA Locations | ✓ 4 locations | 1–2 locations |
| Long-Term Contract | ✓ None required | Often required |
| Retatrutide Available | ✓ Yes | ✗ Rarely offered |
Start your weight loss program at any location — walk-ins welcome.
Everything you need to know about medical weight loss at The Hydro Drip Bar.
Join hundreds of Southern California patients who chose The Hydro Drip Bar for medically supervised GLP-1 weight loss. New clients get their first month of Tirzepatide for just $99.